Controlled & Rx disposal for 340B pharmacies.
Controlled-substance, pharmaceutical, and returnable-Rx disposal built for 340B pharmacies — DEA-compliant destruction, reverse distribution to recover credit, and a Certificate of Destruction every time, with the documentation your program and audits demand.
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340B means extra scrutiny on every dollar.
340B pharmacies manage tight inventory accountability — disposal has to be documented and credit-maximizing.
- Controlled substances (Schedules II–V)
- Expired & unsellable Rx
- Returnable stock for manufacturer credit
- RCRA-hazardous drugs (segregated)
- DEA Form 222 & 41 handled
- Audit-ready documentation
Every 340B pharmacy waste stream, explained.
340B pharmacies live by documentation — reverse distribution recovers credit, and audit-ready records keep your program defensible. Sloppy disposal is both lost money and audit risk. This guide covers every stream and the paper trail that keeps you clean.
Reverse distribution & returns
Recovers credit and produces the documented return records 340B audits expect.
- Expired / unused returnable Rx
- Overstock & discontinued inventory
- Manufacturer recalls
- Brand & generic stock
- Opened / adulterated product (destroy only)
- Patient-owned meds
- Sharps
Controlled substances
Schedule I–V stock and returns, with full Form 222/41 records.
- Expired / unused Schedule I–V stock
- Returns of controls (per program)
- Partial & wasted doses
- Non-controlled meds (pharmaceutical kit)
- Sharps
RCRA-hazardous drugs
P/U-listed and characteristic hazardous drugs — identified and documented.
- P-listed (warfarin ≥0.3%, nicotine, epinephrine)
- U-listed drugs
- Characteristic waste (ignitable, toxic)
- Certain chemotherapy agents
- Non-hazardous pharmaceuticals
- Controlled substances (own path)
Pharmaceutical waste (non-hazardous)
Expired non-controlled, non-hazardous Rx, destroyed with documentation.
- Expired non-controlled, non-hazardous Rx
- OTC & compounded non-haz product
- Samples
- Controlled substances
- RCRA-hazardous drugs
- Sharps
Sharps
From immunization and point-of-care services.
- Immunization needles & syringes
- Lancets
- Point-of-care testing sharps
- Non-sharp meds
- Bloody gauze (biohazard)
We recover credit on returnable Rx and destroy the rest non-retrievable — with Form 222/41 and audit-ready Certificates of Destruction for your 340B records. No contract. Get the full guide (free PDF) →
The 340B Pharmacy's Guide to Compliant Waste Disposal
Recover credit and keep the audit-ready records 340B demands — controls, hazardous & non-hazardous streams. Includes a checklist, cheat sheet & FAQ.
One partner for the 340B waste stream.
Every stream you generate, routed to the right compliant process.
Simple, documented, on your schedule.
Send us your inventory
Scheduled pickup or mail-back for expired and returnable stock, with full documentation.
Fill & seal
Use the labeled containers; segregate each stream at the point of use.
Ship or pickup
Prepaid mail-back label or a scheduled pickup — whatever fits your volume.
Get your COD
We destroy it and email your Certificate of Destruction, archived to your account.
DEA, EPA & 340B documentation.
- DEA-registered reverse distribution & destruction
- DEA Form 222 (Schedule II) & Form 41 handled
- RCRA-hazardous drugs segregated & manifested
- Certificate of Destruction + credit records for audits
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340B pharmacy disposal questions.
How does a 340B pharmacy dispose of controlled substances?
Through a DEA-registered reverse distributor: controls are rendered non-retrievable with DEA Form 41 (and Form 222 for Schedule II), and a Certificate of Destruction is issued — with documentation suited to 340B accountability.
Can 340B pharmacies recover credit on expired Rx?
Yes — reverse distribution sorts inventory into credit-eligible returns (processed for manufacturer credit) and non-returnable stock (compliantly destroyed), which matters under tight 340B economics.
Do you segregate RCRA-hazardous drugs?
Yes. Hazardous pharmaceuticals are segregated and manifested to a permitted facility, separate from your non-hazardous and controlled streams.
Is the documentation audit-ready?
Yes — Form 222, Form 41, chain-of-custody, credit records, and Certificates of Destruction are archived and available for DEA, state, and 340B program audits.
Do you serve contract and specialty 340B pharmacies?
Yes — retail, specialty, and contract 340B pharmacies get the same compliant, documented reverse-distribution and destruction service.
Does reverse distribution help our 340B audit?
Yes — beyond recovering credit, it produces documented return and destruction records that make your program defensible in an audit.
How are controlled substances documented?
With Form 222 for Schedule II transfers, Form 41 for surrendered controls, and a Certificate of Destruction — all audit-ready.
Do you keep records we can pull for audits?
Yes — Certificates of Destruction and return documentation are archived to your account.
Do we need a contract?
No — no contract, no minimums.
Compliant, credit-maximizing disposal for 340B.
Reverse distribution plus controlled and hazardous destruction, fully documented for audits.