RCRA hazardous pharmaceutical waste disposal in South Dakota.
EPA RCRA-compliant disposal of hazardous pharmaceutical waste for Sioux Falls, Rapid City, Aberdeen, Brookings and communities across South Dakota — P-, U-, and D-listed drugs managed under the Subpart P standard, incinerated at a permitted facility, with a manifest and documentation on every order.
Every hazardous drug you need gone in South Dakota.
P/U/D-listed and characteristic waste, manifested and documented.
- P-listed acutely hazardous drugs
- U-listed hazardous drugs
- D-listed / characteristic waste (ignitable, corrosive, toxic)
- Bulk & P-listed chemotherapy drugs
- Hazardous formulary items
- Black-container hazardous waste
Pick a size. We handle the rest.
Prepaid, compliant, and documented — shipped to any South Dakota address.
Single-site practices and clinics in Sioux Falls with routine volume.
Higher-volume South Dakota sites — with an expedited option when timing matters.
Bulk volume, multi-site South Dakota programs, or scheduled pickup.
The RCRA Hazardous Drug Waste Guide
P-, U-, and D-listed drugs, the Subpart P management standard, black-container segregation, and how any facility disposes of hazardous pharmaceuticals compliantly — plus a checklist and FAQ.
Mail-back or scheduled service, statewide in South Dakota.
Order your kit
Black RCRA container shipped to any South Dakota address with a prepaid return label — or set scheduled service for Sioux Falls and higher-volume sites.
Segregate hazardous drugs
Place P/U/D-listed and characteristic drugs in the black container — keep non-hazardous meds in the pharmaceutical stream.
Ship or pickup
Manifested and tracked door-to-door to a permitted TSDF under DOT and EPA rules.
Get documentation
Incinerated at a permitted facility; your manifest and record are archived to your account.
South Dakota & federal RCRA rules, handled.
Some drugs are also hazardous waste under the EPA's Resource Conservation and Recovery Act (RCRA, 40 CFR). They fall on the P-list (acutely hazardous), U-list, or exhibit a characteristic (ignitable, corrosive, reactive, toxic — the D-codes). Healthcare facilities manage them under the Subpart P standard for hazardous waste pharmaceuticals. In South Dakota, the South Dakota Department of Agriculture & Natural Resources (DANR) — which may be more stringent than the federal floor — and the South Dakota Board of Pharmacy add requirements. Easy Rx Cycle identifies, segregates, manifests, and destroys each hazardous drug correctly, documented on every order.
- EPA / RCRA: P-, U-, and D-listed hazardous waste (40 CFR)
- Subpart P: hazardous waste pharmaceuticals management standard
- Manifest: hazardous waste manifest & permitted-TSDF incineration
- South Dakota: state environmental (often stricter) & Board of Pharmacy rules
- Environmental regulator
- South Dakota Department of Agriculture & Natural Resources (DANR)
- Pharmacy oversight
- South Dakota Board of Pharmacy
- Statewide drug take-back law
- No statewide take-back law — disposal via mail-back kits, pharmacy kiosks & DEA collectors
- Home sharps in household trash
- Allowed only in an approved, puncture-resistant container, subject to local rules
South Dakota healthcare footprint: roughly 116 pharmacies, 60 hospitals, 312 physician offices, 319 dental practices, 96nursing & long-term-care facilities, and 151 veterinary clinics — every one a generator of regulated waste we serve. Source: U.S. Census County Business Patterns, 2022.
Federal rules (OSHA 29 CFR 1910.1030, DOT 49 CFR, EPA RCRA, DEA 21 CFR 1317) apply in South Dakota on top of the above.
Built for South Dakota facilities with a hazardous formulary.
RCRA Hazardous Pharmaceutical Waste Disposal in South Dakota: questions.
What is RCRA hazardous pharmaceutical waste in South Dakota?
Drugs that are also hazardous waste under EPA rules — P-listed (acutely hazardous), U-listed, or characteristic (ignitable, corrosive, reactive, toxic). Common examples include warfarin, nicotine products, and certain chemo drugs. We manage them under Subpart P across South Dakota, and serve Sioux Falls, Rapid City, Aberdeen, Brookings.
What's the difference between P-, U-, and D-listed drugs?
P-listed drugs are acutely hazardous (strictest handling), U-listed are hazardous but non-acute, and D-listed (D-codes) exhibit a characteristic like toxicity or ignitability. Each has specific South Dakota handling and documentation — our guide breaks them down.
What is the Subpart P standard?
40 CFR Part 266 Subpart P is the EPA's management standard for hazardous waste pharmaceuticals at healthcare facilities and reverse distributors. It sets how these drugs are accumulated, labeled, and shipped. We keep your South Dakota program aligned to it.
Who regulates hazardous drug waste in South Dakota?
The EPA under RCRA federally, plus South Dakota's state environmental agency — which is often stricter than the federal floor — and the Board of Pharmacy. The DOT governs transport. We handle disposal and the manifest to all of them.
Do you serve Sioux Falls and the rest of South Dakota?
Yes — mail-back reaches every ZIP in South Dakota, from Sioux Falls to Brookings, and scheduled service is available for higher-volume sites across the state.
Manage hazardous drug waste right in South Dakota.
Order a compliant RCRA kit in minutes, or get a same-day quote for scheduled service across South Dakota.